Protein tạo hình xương 7

Quá trình sinh học

UniProt


P18075

Bản thể genChức năng phân tửThành phần tế bàoQuá trình sinh học

Bản thể gen
Chức năng phân tử	• heparin binding • cytokine activity • transforming growth factor beta receptor binding • growth factor activity • BMP receptor binding • GO:0001948 protein binding
Thành phần tế bào	• extracellular region • Cấu trúc nền của da • extracellular • Túi tiết • collagen-containing extracellular matrix
Quá trình sinh học	• eye development • pattern specification process • skeletal system development • ureteric bud development • negative regulation of neuron differentiation • embryonic pattern specification • mesenchyme development • anatomical structure formation involved in morphogenesis • negative regulation of cell cycle • mesonephros development • odontogenesis of dentin-containing tooth • mesenchymal cell differentiation • negative regulation of mitotic nuclear division • animal organ morphogenesis • metanephric mesenchyme morphogenesis • metanephros development • cellular response to hypoxia • regulation of pathway-restricted SMAD protein phosphorylation • regulation of removal of superoxide radicals • steroid hormone mediated signaling pathway • negative regulation of Notch signaling pathway • negative regulation of cell proliferation • branching involved in salivary gland morphogenesis • regulation of apoptotic process • SMAD protein signal transduction • ossification • kidney development • negative regulation of cell death • tube morphogenesis • positive regulation of transcription, DNA-templated • negative regulation of prostatic bud formation • cartilage development • embryonic limb morphogenesis • negative regulation of MAP kinase activity • embryonic camera-type eye morphogenesis • positive regulation of neuron differentiation • positive regulation of cell differentiation • negative regulation of phosphorylation • regulation of branching involved in prostate gland morphogenesis • Biệt hóa tế bào • neuron projection morphogenesis • nephrogenic mesenchyme morphogenesis • positive regulation of heterotypic cell-cell adhesion • epithelial cell differentiation • response to vitamin D • positive regulation of hyaluranon cable assembly • positive regulation of bone mineralization • dendrite development • negative regulation of neurogenesis • regulation of phosphorylation • BMP signaling pathway • positive regulation of osteoblast differentiation • epithelial–mesenchymal transition • negative regulation of transcription, DNA-templated • negative regulation of NF-kappaB transcription factor activity • branching morphogenesis of an epithelial tube • negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis • negative regulation of glomerular mesangial cell proliferation • response to estradiol • monocyte aggregation • metanephric mesenchymal cell proliferation involved in metanephros development • positive regulation of cell death • cell development • negative regulation of striated muscle cell apoptotic process • positive regulation of pathway-restricted SMAD protein phosphorylation • mesoderm formation • response to peptide hormone • cellular response to BMP stimulus • positive regulation of dendrite development • salivary gland morphogenesis • axon guidance • multicellular organism development • positive regulation of peptidyl-threonine phosphorylation • positive regulation of apoptotic process • protein localization to nucleus • embryonic skeletal joint morphogenesis • camera-type eye morphogenesis • positive regulation of transcription from RNA polymerase II promoter • endocardial cushion formation • pericardium morphogenesis • neural fold elevation formation • hindbrain development • cardiac muscle tissue development • pharyngeal system development • cardiac septum morphogenesis • chorio-allantoic fusion • heart trabecula morphogenesis • allantois development • positive regulation of epithelial to mesenchymal transition • positive regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis • regulation of receptor activity • positive regulation of gene expression • negative regulation of NIK/NF-kappaB signaling • regulation of MAPK cascade
Nguồn: Amigo / QuickGO

Kết thúc

57,266,641 bp [1]

Loài

Người

Chức năng phân tử

• heparin binding
• cytokine activity
• transforming growth factor beta receptor binding
• growth factor activity
• BMP receptor binding
• GO:0001948 protein binding

RefSeq (protein)


NP_001710 NP_001710.1

Danh pháp

BMP7, OP-1, bone morphogenetic protein 7

RefSeq (mRNA)


NM_001719

ID ngoài

OMIM: 112267 HomoloGene: 20410 GeneCards: BMP7

PubMed

[2]

NST

Nhiễm sắc thể 20 (người)[1]

PDB

Tìm trên Human UniProt: PDBe RCSB

Thành phần tế bào

• extracellular region
• Cấu trúc nền của da
• extracellular
• Túi tiết
• collagen-containing extracellular matrix

Vị trí gen (Người)NSTBăngBắt đầuKết thúc

Vị trí gen (Người)

NST	Nhiễm sắc thể 20 (người)[1]

Băng	20q13.31	Bắt đầu	57,168,753 bp [1]
Kết thúc	57,266,641 bp [1]

Danh sách mã id PDB

Danh sách mã id PDB
1BMP, 1LX5, 1LXI, 1M4U

BăngBắt đầu

20q13.31

Ensembl


ENSG00000101144

Entrez


655

Vị trí gen (UCSC)

Chr 20: 57.17 – 57.27 Mb

Cấu trúc được biết đếnPDBDanh sách mã id PDB

Cấu trúc được biết đến

PDB

Tìm trên Human UniProt: PDBe RCSB

Danh sách mã id PDB
1BMP, 1LX5, 1LXI, 1M4U